On 19 September 2020, the Coordination Committee of SISMIKO, one of the Emergency Operational Groups (GO) of the National Institute of Geophysics and Volcanology (In italian: Istituto Nazionale di Geofisica e Vulcanologia, INGV), met to evaluate an intervention by the mobile seismic network in Eastern Sicily. In the previous days some seismic events, located near the municipalities of Salemi, Vita and Gibellina in the province of Trapani, were troubling the localadministrations. The Head of Civil Protection of the Sicily Region therefore asked the president of the INGV for an assessment of the intensification of the seismic monitoring of the area. At the time of the convocation of the Coordination Commitee there were about 10 events of magnitude M, between 1.3 and 3.5 M; four of these earthquakes had been felt by the population. After the meeting, the decision has been taken to activate SISMIKO and to install a temporary network made up of 4 seismic stations. The data of the stations, transmitted in real time to the INGV acquisition centers of Catania (Osservatorio Etneo, OE) and Rome (Osservatorio Nazionale Terremoti, ONT), were integrated into the system to contribute to the national seismic surveillance services that are carried out at the ONT Operations Room. This work describes the main activities carried out by SISMIKO, starting from the convening of the Coordination Committee to the uninstallation of the infrastructure.