Hyperspectral spaceborne, airborne and ground measurements campaign on Mt. Etna: multi data acquisitions in the frame of Prisma Mission (ASI-AGI Project n. I/016/11/0) n the frame of the Italian Space Agency (ASI) Hyperspectral Mission PRISMA (Precursore IperSpettrale della Missione Applicativa), the Istituto Nazionale di Geofisica e Vulcanologia (INGV) is coordinating the scientific project ASI-AGI (Analisi Sistemi Iperspettrali per le Applicazioni Geofisiche Integrate) to develop specific algorithms and products for various geophysical applications. The data validation and calibration activities have been focused on three active volcanic areas located in Sicily: Mt. Etna, Paternò and Ciclopi islands. From June 23 until 27, 2012 INGV and the project partners have organized an airborne and ground campaign over the selected test sites covering different surface targets. The airborne data were acquired by using a SPECIM sensor working in the VNIR-SWIR range and jointed to an airborne laser scanner and a thermal camera. The ground campaign has allowed to collect several datasets using two portable spectroradiometer (Fieldspec), two portable Fourier Transform InfraRed spectrometer (FTIR), a ground laser scanner, a thermal camera and a TIR thermometer. Moreover, in order to acquire local atmospheric parameters a sun photometer and a meteorological station have been used as well as further meteorological information have been furnished by CETEMPS L’Aquila University. During the airborne and ground campaign the contemporaneous acquisitions of Hyperion and ASTER have allowed to extract a suitable data set that will be used to simulate PRISMA data and to develop and test the proposed algorithms for a large number of applications regarding for example land cover and agriculture, water quality monitoring, surface hydrology, urban areas monitoring, geology, security, desertification, territory monitoring to support to natural hazard management, atmosphere monitoring for its optical and spectral characterization, carbon cycle.